Cannot save copies of PDF files on Mac

Every time I try "Save as Copy" it returns error message "There was a macintosh system error (-5000)", or sometimes the error number is (+5000).
I've searched for help but cannot find any reference to this error message. The files have no security settings.
Any help would be gratefully received.
Adobe Reader v9.4.1
Mac OS X v10.6.6
Thanks!
Em

happyem wrote:
I've never repaired disk permissions on this Mac - do you think it will help?
For an error of that sort, it might. Certainly won't hurt.
As an aside, I tent to repair disk permissions before and after any large(ish) install. Especially system updates. It'll keep your Mac healthy.
Also it doesn't hurt to leave it on overnight and on occassional weekends so it can run repair scripts or use a third party utility like Onyx to run them when you want. You can also repair disk permissions with Onyx.

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