Cannot save file after opening in photoshop

I have a file selected in my lightroom library and I select photo -> edit in photoshop. I am selecting to edit a copy of the file. A copy is created and opens in photoshop. I make some adjustments and when I try to save it, I get an error message:
Could not save "file name" because the file is already in use or was left open.
I tried closing lightroom before saving, but it did not help.
All these in lightroom 1.3.1 and photoshop cs3 on a mac.
Any suggestions?
Thanks in advance

Hi...yes I can do a file Save As... but only as a different name, it will not replace the current name (says file open, same as before). If I do Save As and use a new name of course, I am then left with the original PSD file and the new one (which is not in the LR catalog, must be imported.)
The files are not open in bridge, it isn't even running.
Thanks
Dave

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