Cant copy from External Drive get error Code 50

I have a Mac Pro and suddenly it won't copy files from any external drive, or write them either. The drives mount and show up in fiinder, and they start copying, but after about 30 seconds they error out with "The operation can't be completed because an unexpected error occurred (error code 50).
It has done this on two different Mac Pros and 3 different external drives.  I don't remember this haqppening before. I have Paragon NTFS running on both Macs and they have worked flawlessly for maqny months but now they won't complete.  Any help would be appriciated.
[email protected]

Please read this whole message before doing anything.
This procedure is a diagnostic test. It’s unlikely to solve your problem. Don’t be disappointed when you find that nothing has changed after you complete it.
The purpose of this exercise is to determine whether the problem is caused by third-party system modifications that load automatically at startup or login. Disconnect all wired peripherals except those needed for the test, and remove all aftermarket expansion cards. Boot in safe mode and log in to the account with the problem. The instructions provided by Apple are as follows:
Be sure your Mac is shut down.
Press the power button.
Immediately after you hear the startup tone, hold the Shift key. The Shift key should be held as soon as possible after the startup tone, but not before the tone.
Release the Shift key when you see the gray Apple icon and the progress indicator (looks like a spinning gear).
Safe mode is much slower to boot and run than normal, and some things won’t work at all, including wireless networking on some Macs.
The login screen appears even if you usually log in automatically. You must know your login password in order to log in. If you’ve forgotten the password, you will need to reset it before you begin.
Test while in safe mode. You'll only be able to read, not write, an NTFS volume. Same problem(s)?
After testing, reboot as usual (i.e., not in safe mode.)

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