Cant start photoshop, after effects, or premiere pro?! e.i. "Cant find AfterFX.exe"

When i try to start these programs, it says:
"The program can't start because C:\program iles\adobe\adobe photoshop CC 2014\photoshop.exe is missing from your computer. try re-installing the program to fix this problem."
This happens with each of them. I have re-installed 3 times and i still get this. I even manually found it and it still wont start. i tried going to Adobe's folder in appdata and changing it read and write, because that was a possible solution on one website. Besides that, i couldn't find any other website, talking about this problem. I also ran a full virus, malware scan.
Please help! i want to use this!!

When i try to start these programs, it says:
"The program can't start because C:\program iles\adobe\adobe photoshop CC 2014\photoshop.exe is missing from your computer. try re-installing the program to fix this problem."
This happens with each of them. I have re-installed 3 times and i still get this. I even manually found it and it still wont start. i tried going to Adobe's folder in appdata and changing it read and write, because that was a possible solution on one website. Besides that, i couldn't find any other website, talking about this problem. I also ran a full virus, malware scan.
Please help! i want to use this!!

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    Thanks all. I have just tried a few things, installing them onto the C drive as you all specified as not being one of them. I can understand it, but at the same time i have a classmate who has their software on a seperate drive and it runs smoothe. I'm on my second GPU in 2 weeks, unless I have terrible luck it seems doubtful being that I can run games and a majority of the software no problem. Through further testing around with a corded mouse and keyboard I've noticed the following...
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