Changed Internal HD - Now Photoshop won't load: "Could not initialize.."

Hi All,
I apologise for posting here.. I've been trawling the Adobe forums and none of the suggestions for this seem to work.
I recently used Carbon Copy Cloner to take a copy of my 80gig HD and transfer it to my new 320gig HD (internal) that I have upgraded within my MacBook.
So far everything, other than Photoshop, is working fine. Unfortunately, when I try to run Photoshop (CS2), I get the following error:
"Could not initialize Photoshop because the disk is not available".
It seems that my transfer of data has somehow buggered up the scratch disk. Interestingly, imageready and illustrator both load and run okay but not photoshop.
I have followed the advice in this thread:
http://discussions.apple.com/thread.jspa?messageID=6804821
That basically stated:
1) Repair Permissions on your startup drive.
2) Delete Photoshop's preferences. In the Preferences folder of your user account, delete the entire folder, "Adobe Photoshop CS3 Settings".
3) Download and apply the 10.4.11 Combo updater. Repair permissions both before applying the update and after. Delete Photoshop's preferences before trying to launch it.
With the exception that I downloaded and applied the 10.5.5 combo updater....
However, while this solved the problem for the previous person, this has not rectified the issue for me.
Any advice greatly appreciated.

I uninstalled the CS2 suite to reinstall from scratch. Bad move. Looks like CS2 does not install in Leopard and is no longer supported by Adobe.
Epic Sigh. Keeping up with the releases of Adobe products is a never-ending race. (Insert the word expensive somewhere in that sentence).

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Changed Internal HD - Now Photoshop won't load: "Could not initialize.."

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