Communication issue between SAP and VERTEX

Hi All,
We are facing connectivity issue with our Intergration system and vertex and below is the error message from SM59.Development and production seems to work fine.Kindly help check.
Logon     Cancel
Error Details     timeout during allocate / CPIC-CALL: 'ThSAPCMRCV' : cmRc=20 thRc=456 Timeout dur
Error Details     ERROR: timeout during allocate
Error Details     LOCATION: SAP-Gateway on host ssapeci / sapgw04
Error Details     DETAIL: no connect of TP /sapmnt/ECI/vertex/translink/verrfc from host ssapeci
Error Details     COMPONENT: SAP-Gateway
Error Details     COUNTER: 3114
Error Details     MODULE: gwr3cpic.c
Error Details     LINE: 6266
Error Details     RETURN CODE: 242
Error Details     SUBRC: 0
Error Details     RELEASE: 700
Error Details     TIME: Wed Mar 31 10:42:18 2010
Error Details     VERSION: 2
AIX - 6.1
Oracle version - 10.2
SAP version - SAP ECC 6.0
Edited by: Priyanka Singh on Mar 31, 2010 12:50 PM

Hi my friend
1. Create a TCP/IP Connection RFC <connection> in SM59:
activation type: registered server program
program ID: <program>
2. Create an ini file in directory /usr/sap/<SID>/SYS/profile with content:
DEST=<connection>
TYPE=R
PROGID=<program>
GWHOST=<hostname>
GWSERV=sapgw<nn>
RFC_TRACE=0
Regards,

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