Constantly receiving Error -43 when backing up iPhone

When trying to upgrade my iPhone from 4.1 to 5 in iTunes 10.5 on my Windows 7 x64, the update process begins by trying to backup the iPhone. Every time it tries, however, it gets a small way into backing up the iPhone, it appears with the error box: "An error occurred while backing up this iPhone (-43)" and tells me that continuing will erase the phone. This happens every time.
Bizarrely, right-clicking the device in the navigation pane and choosing Back Up *seems* to work fine, but it is waaayyy too fast, so I dont think the backup is working properly.
I have enough hard drive space to store the entire device, so that shouldnt be a problem.
I dont want to have to Restore or Erase the device because it has a lot of information and I dont think the Backups are valid.
Anyone have any ideas?

Well, I've since taken the plunge and tried to update anyway, by restoring the iPhone, thinking I could restore from my backups. Now turns out that I can't restore because "the backup session failed". Goddammit.
This is the biggest problem I have with my iPhone, that iTunes is such an abominable piece of software. I just want to get iOS 5 on this phone so I can leave iTunes behind.

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