"Could not open scratch file because disc is not available" Mac

I recently changed the Photoshop (CS6) Scratch Disk choice from the default Boot Drive to one of the other internal drives in my MacPro (OS 10.6.8).
When I restart Photoshop (CS6) I get the message:
"Could not open scratch file because disc is not available"
and Photoshop will not launch.
I then restart Photoshop with "Command - alt - shift" keys held down
(as per suggestion at <http://forums.adobe.com/message/3937003>)
and reset the preferences which allows Photoshop to come back.
(Resetting preferences returned the Boot Drive to scratch disk status.)
I have another MacPro that - same OS 10.6.8 and Adobe CS6 - and I don't have this scratch disk allocation problem.
What is going on with the one  MacPro that prevents me from selecting a Photoshop scratch disk other than the boot drive?

Ignore Ownership worked. Thank you!
I saw this suggestion on another Discussion thread but wondered if that could be the problem since the non-boot scratch disks used on other computers here do not have this property chosen.
"Permissions", "Ignore Ownership", and "apply to enclosed items" remain a mystery to me.
As for Terminal, I've had my hand held a couple of times while I went there and it was not a comforting experience.
Our work setup depends on complete access by everybody to everything (Read&Write Privileges apply to everyone here). We occasionally swap drives between computers which may cause problems, but why should it and how am I to know. The computer that prompted this discussion had its main hard drive replaced a couple of months ago which may have contributed to the problem.
Is there a down-side to ignoring ownership on everything and having "read-write" privileges apply to everyone (aside from lax security)?

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    Could not open a scratch file because the file is locked or you do not have the necessary access privileges. (…) | Mylen…
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    could not open scratch file because the file is locked or you do not have the necessary access rights.

    It means what it says: Check your file permissions on your scratch disk.
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