Could not save because file was already in use or left open

I am have several problems with Adobe Photoshop CS4. I call up Adobe for help, I pay 50.00 or 60.00 for their help with these situations that I am having. Adobe concludes the phone call saying they are closing the case cause the problem has been resolved. I told them it has not been resolved I am still having problems then the person hangs up on me. I call back cause the problems still persists, the tech person told me that I had to pay another 50.00-60.00 for the
tech support. I told him that I already paid and that I still need help, the tech guy told me that the case was closed cause it was resolved. I told them it was not
resolved and I am needing help with this particular issue. The tech person kept saying that the issue was resolved and if I needed more help that I had to pay.
This time I hung up on him and while I did that I said that the Apple Support Community was way more helpful and it was free.
So here I am 6 months later and tried everything, Here are the problems that I am having.
1. CS4 keeps quitting unexpectedly with no cause no error nothing. The blue light under the CS4 Ps is still lit and wont let me reopen the file, I then have to force quit the program. I then get these windows asking if I want to send a report, I click ignore cause I am tired of filling out those things. So I try to open the
photoshop file and I get the blue window with the Ps logo on it, its scanning everything but then it stops responding when the scan reaches the part where it says scanning memory and freezes. I then have to force quit the program again, I have to do this 5 times before it will open the file. Then Ps will unexpectedly quit after 2 hrs of working and starts the B.S. all over again. I dont know what is wrong with CS4. Other times it runs really slow and glitchy. It also happens on my Mac Book Pro, iMac and of course my Mac Pro.
I know its not the computers or the settings or anything interacting with it. I checked everything extensively from the terminal to permissions and back to the program itself and everything in between. I am needing help, the Adobe forums are of no use, I cant find anything there.
2. I keep getting this error and I am not sure what it is, this only happens when I use Ps CS4 and yes it happens on all my other Apple computers.
Error: "could not save because file was already in use or left open" not sure how to fixt this, I have already tried the permissions and it did not seem to work.
All my computers run OS X Lion version 10.7.3. I had these problems even before I upgraded to Lion, 2 months later after Lion came out. These problems have been going on since Snow Leopard. All my Macs are up to date and I did use the Disk Utilities on everything... Please help me.

First off are you editing a photo that you have placed into indesign if so the in use or left open issue is a common one, the only help is to go to indesign move the picture by nugging it then go back to photoshop and try saving again, if this does not work close the indesign file then save.
On the other issue of photoshop crashing, One thing I would try would be to create another user account, Start up photoshop and only it and work with it. The reason why is to see if maybe there are some 3rd party software you have loaded on your systems that might be causing the issues. "Ya never know"
I would assume you have reinstalled photoshop on lion. Do you still have older version of OSX installed, if so try booting to them and working with photoshop to see if it works there.
Good Luck

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