Couldnt predict the error..

Hi friends,
I configured email with APEX 4.0 for sending mail from APEX...
I have obtained this successfully only for a quite period of time...
These are my SMTP host address : 172.16.1.45 and port 25..
These are the settings that i have done before, and this worked perfectly...
Now my SMTP host address is changed to 172.16.1.30, so in place of 45 i have changed it to 30...
Now my mail is not going from APEX...
Since i have also enabled network services as im using DB 11g.....
Now what the error that im facing soon after changed it to 172.16.1.30, is
ORA-29278: SMTP transient error: 421 Service not available
The above is the error that im getting for the corresponding mail that i send from APEX in the MAIL QUEUE...
But now what the problem is if, i logged out of the admin page and again if i logged in means, now there is no any mails in the MAIL QUEUE...I thought that the mail was send..
But the receipient still didnt receive any mails....
If the mail is not send via APEX means, it will be in the MAIL QUEUE with corresponding error...But my problem is soon after sending mail it is accumulating in the QUEUE with SMTP error...But after 10 minutes if i logged out and again logged into the QUEUE means there is no any mail in the QUEUE..
But not receiving yet..
I couldnt predict with this problem...What may be the issue over here friends,
Thanks
Saro..

Hi friends,
I was wrong with the new IP address of my SMTP as it was not 172.16.1.30 but it is 172.16.1.25...
Soon after i made that change i received an error like
>SMTP Error: Unable to relay with [email protected]
Soon after adding my machine to the relay list of the Server, now i can send email through APEX..As it is of my mistake...
Thanks
Saro...

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