CS 5.1 Mac....  Could not initialize Photoshop because of a program error.

CS 5.1 Mac....  'Could not initialize Photoshop because of a program error.'
I changed my security preferences and still get the same thing poping up.  I am not able to open PS CS5.1 on my mac.
What should I do or even where do I go if I need to re-install CS 5.1? I have my Lic#
MikeNewsome.com

I don't think the application installation would be corrupt because I uninstalled and re-installed according to adobe and all the times I did so, it was from adobe website.  and I am thinking about the OS, if that were corrupt, a lot more applications, ... would be giving me problems.
It is only PS. I am almost at wit's end trying to solve this issue. I would have thought re-insatlling program (prob did this about 10 times), would solve any issues.  I did use the cc cleaner but only yesterday as a last resort. I just don't know where to go with this problem.
when 1st happened I just uninstalled and reinstalled a few times and when that didn't solve anything, also then ran utility programs a few times.all the while deleted prefs

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