CS3 crashing in Vista (comdlg32.dll)

Question

I have a problem with Photoshop CS3 on vista home premium (32bit). Each time I try to save an image (either using the keyboard shortcut or selecting from the edit menu) Photoshop immediately crashes (with no error message). If I close the image I get a dialog box that states, "Adobe Photoshop CS3 has stopped working". If I display the problem details box, I see the following:
Problem Event Name: APPCRASH
Application Name: Photoshop.exe
Application Version: 10.0.1.0
Application Timestamp: 470fd6cb
Fault Module Name: comdlg32.dll
Fault Module Version: 6.0.6001.18000
Fault Module Timestamp: 4791a752
Exception Code: c0000005
Exception Offset: 0002ab06
OS Version: 6.0.6001.2.1.0.768.3
Locale ID: 2057
Additional Information 1: fd00
Additional Information 2: ea6f5fe8924aaa756324d57f87834160
Additional Information 3: fd00
Additional Information 4: ea6f5fe8924aaa756324d57f87834160
I've tried running in XP compatibility mode (I had no problems when I had XP SP2 installed), but the problem is exactly the same.
Is it possible that the comdlg32.dll file is corrupt? I can't find any other mention of this problem. No other applications seem to be affected by this.
Many thanks in advance

Answer 1

Yes, most likely that means that comdlg32.dll is corrupt.
It could also mean some malware, or some other DLL/process interferring with things.