CS3 Serial Number doesn't hold (network accounts)

Question

I work for a school and we recently purchased Photoshop CS3 (w/ a 30-user site license) for our students to use in the computer graphics (CG) lab (all intel macbooks). We created an image with PS on it (along with the serial number, done as an admin) and applied the image to all CG computers. We also use a file-management system called Filewave to push out updates en masse instead of applying updates to individual machines.
When the students first started using the program it worked fine, no problems. They logged into their network accounts and PS ran great. However, and I'm not sure about this, but when the 10.0.1 update came through, it knocked out the serial number. Now, every time a student wants to use PS, he/she has to enter the serial number (the teacher has it in big letters up on the chalkboard, permanently).
Since that happened, I've seen it happen on two other machines (another macbook and a brand new iMac) but they are both on network (mobile) accounts. I've got CS3 on my machine and my principal has it on his (macbook pros, neither are networked) and we haven't had any problems.
I've been working on one of the CG macbooks through an admin account to try to figure out what the problem is. I did a clean uninstall (I think...the Adobe Uninstaller tool has never worked -- I get a JavaScript Alert - installer database invalid -- so I used the mac CS3Clean tool provided by adobe and deleted anything related to adobe - a mistake??). When I reinstalled the software, it installed without any errors and it took the site serial number. I restarted the machine and shut it down, and was able to get into PS without a problem. As soon as I apply the 10.0.1 update and restart, I get the prompt for a serial number again. I did another clean uninstall and reinstall, and now even without the update I get prompted for the serial number every time ( I haven't even logged into a network account yet).
So now I come to you! Has anyone ever come across this problem? Is there a bug in the 10.0.1 update that won't let the serial number "stick?" Any ideas on this one? Is there a problem using this on network accounts? Any help is welcome!
Thank you.

Answer 1

Got it! After spending around 3-4 hours on the phone with Adobe, we found out that the file that holds the serial number info (cache.db) was being replaced by our FileWave software. So when you enter the serial number into the adobe SN prompt, it modifies the cache.db file and allows a user to keep using PS. After a restart however, our file-maintenance software sees that there is a change to that file and promptly replaces it with an older version, thus eliminating the PS serial number.
At first this seemed kind of strange since we did not set FileWave to touch any PS files. Then we found out that Adobe Reader uses the exact same file to store its information in (which FileWave was set to maintain). So, we turned off all maintenance on Adobe products and now we are having no serial number issues. The chalk can now be erased from the proverbial blackboard. In retrospect, it looks like the 10.0.1 update had nothing to do with anything, it just turned out to be coincidental timing.
Thanks for all of your help!