CS5.5 query and programmes not opening any more

I put CS5.5 InDesign onto a Mac yesterday (iMac 27” running 10.6.8) and
since then machine has just about stopped working. Done lots of things like
repair permissions (lots of times, including repair from original system
disk as well). Most of the programmes just don’t open, they might bounce
once and that’s it.  Yet strangely enough ID will open, but Acrobat wont
open, lots like Safari, Entourage, Word wont open.
Tried a new user and the same. Yet in Safe Mode it seems to open programmes
happily. Have looked in Console (which only opens in safe mode!) and cant
say I can see anything really obvious in errors. Have thrown away some
preference files and for brief moment seemed to work. Have had a look on
apple and adobe forums and cant see much obvious than always repair
permissions again! Saw something about Suitcase Fusion which we use and auto
activation of fonts which was turned off anyway.
I have run out of ideas now and hoping someone might have a suggestion of
something else to try, installed the same disk onto my iMac on 10.7.3 and
its working fine

Spent few more hours trying to fix my problem and it turned out
to be some 'LaunchAgents' and LaunchDaemons' that were giving me the
problems - not just sure which one it was as deleted a few but wasted much
longer that I would have liked trying to fix it and read loads of forum
messages that thankfully gave me the answers I needed !

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