CS5 InDesign cannot open files in the InDesign CS5 document format

I'll be working in InDesign CS5 with no problems then at some point I'll double click on an InDesign file and a window comes up and says - InDesign cannot open files in the InDesign CS5 document format. Sometimes when this happens I have to completely reboot my whole system before I can get InDesign to function correctly. Is this a flaw with CS5? Did not happen with previous versions. It doesn't always happen but I can't figure out what causes it. Would appreciate anyones help. I'm getting to really HATE InDesign!!

I have not uninstalled and reinstalled, but I did just switch over to another workstation using Time Machine. The previous system was Leopard. This one is running Snow Leopard.
I'm not sure how to parse this. When you say "switch over to another workstaiton using Time Machine" do you mean, "started using another machine that happens to be using Time Machine for backups and is also running 10.6 instead of 10.5"?
Or do you mean, "Used the Time Machine program to upgrade from 10.5 to 10.6?" If you mean the second one, well, I can't say I am surprised that things are messed up. And that would make your problem rather different than the other posters, which is good reason for you to have started your own thread (and thus your own solution)....
I'm a little bit leary of getting in and changing things in Terminal, without understanding what I am changing. Plus this is a workstation at work, so if I screw something up, that is not a good things, and I don't have time to spend a day fixing things back up again, with the way our workload is.
Well, you can find a lot of marginal documentation about lsregister and Launch Services, but I wonder whether your understood the ramifications of messing with Time Machine (or maybe I have misinterpretted you!). I'd be surprised if you found another way to fix this, other than uninstall/reinstall.
Good luck.

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