CS5 Premiere was working perfectly until last night... Now not responding. Any solutions?

Hey all,
So, for the past month I've had no problems editing with premiere. Then last night while editing on a much smaller project than normal, (same file types) the program started slowing down, considerably. Now, any keystroke puts the program into "not responding" and it takes minutes to select clips. I've restarted the computer, program, and looked at my cpu usage in the task manager. While the program is running, and then not responding, the computer is not stressing at all, 14% cpu, 31% memory. 
Im running an i7 [email protected], 8gb ram, with ati hd 5770.
What i dont understand is why I've had no issues until last night, and now I cant use the product at all. My After Effects still works fine at least.
Any one else have this issue or know of a fix?

Along with TClark's questions, try doing a New Project, and test it out.
There have been reports of Project files bloating, and then not working properly. Adobe is working on that. Seems that many/most/all of those came with CS4 Projects converting to CS5. Was there any CS4 to CS5 conversion anywhere in this workflow?
Good luck,
Hunt

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