CS6 panels hang + Prefs keep resetting...Help!

I've been using CS6 for over a year and no issues. I upgraded to Lion, no issues. Then two weeks ago InDesign started going wonky:
- right-side panels will not open upon clicking for 20-30 seconds, very laggy and make it impossible to work.
- Every time I turn off my system, my InDesign preferences re-set to default (Except for default font, that stays the same).
I've looked through the forums and no solution seems to apply.
My system:
OS Lion 10.7.5
2.93 GHz Quad-Core Intel Xeon
16 GB DDR3
I use Suitcase Fusion 4, and have been since installing CS6...no new plugins installed since issue started.
Thank you much!

Well, it's now May and we have been busy at work and haven't had time to post on this issue anymore. I uninstalled all 3rd party plugins but to no avail. I am still having this same issue. I have also tried all of the above mentioned. The only thing that I haven't done yet (and may do this weekend) is uninstall/reinstall..... Anyone else having this issue?

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