CS6 Won't open files - Program Error

When I try to open files in CS6, I get an error "Could not complete your request because of a program error."     I have restarted PS and rebooted the machine.
Running Mac OS 10.6.8
2.8 GHz   Core i7
12 GB Ram
The same files open fine on CS5.

Chris,
There are no log files in the settings folder.
Curt,
I have the "Open in CS6" available in Bridge.   When I open a jpg from Bridge, same PS error.  If I open a CR2 in ACR, ACR is fine, but when I tell it "open image" (in ACR), ACR closes, and nothing happens in Photoshop.  No message.  If I double-click a CR2 image from bridge, I get the PS error.
Howard,
Same error regardless of file type.
Thanks for the help.

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