Desk top locked up while using I photo, can't get mouse to do anything more them move. Just on off button works. Any ideas?

Anyone have any ideas on how to unlock the desk top?

Whoah boy, lots of things here and I have to make supper...
I'll choose a few at a time. "RAM drives"
RAM drives? Do you mean hard drives? Do you mean RAM chips?
If hard drives, did you put them back in the same order? Multiple hard drives in one machine often need to be jumpered correctly when you move them about.
If chips... It's too difficult at this stage to tell if it is hardware or software. If hardware it could be chips, and that error at the end had a vague chip ring to it. One way to test for chips if you have extra chips is to pull all but the minimum required to boot and see if it boots.
You mention a backup drive. This wouldn't happen to have a clone of the operating system on it would it?
4 drives... All internal?
From all you've said it could be hardware or software. Blue screen could be software but failing hardware can corrupt a drive, messing up the software.
Boot discs. It sounds like you have no boot discs (CD. DVD) for this computer, right?
What computer are you using right now?

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