Disc error -43 occurred while reading or writing to a scratch disk.

"Disc error -43 occurred while reading or writing to a scratch disk.  Sorry, but this error is unrecoverable."
What does this mean, and how can I fix it?
I assume it affecting my performance if PS is not able to write to the scratch disc???
I get the error every time I shut down Photoshop.
Attached are my settings.

It means that the OS says there was an error with your hard disk.
You need to check the disk for problems, and make sure you have your data backed up before continuing.
It could be a one time thing (especially if the SMART system remapped the bad block), but could also be an indication of serious problems with the disk if it recurrs.

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