Disk i/o error on sleep wake ONLY

Question

I'm having a currious and worrisome problem. For the past few weeks I've been inindated by a problem where after waking from a lengthy sleep, my late 2011 MBP will hang for about 5 minutes with a spinning beachball. I checked the console error log and notice a number of "kernel[0]: disk0s2: I/O error" lines. Of course, my first thought was that this was a physical hard drive failure. However, I've found that after this innitial wait, the computer will run for hours, even perform huge HDD seek and write tasks and produce absolutely no other disk errors, running perfectly smoothly. If this truly was a hard drive failour, wouldn't I be experiencing disk i/o errors fairly consistantly?
Another curious thing, before every batch of disk errors, I've noticed that I get a:
"ATSFindFolder timeout. (domain:-32763, dirType:'font', createFolder:false, ATSServer pid:162)"
This may be quincidence and simply the specific task performed during sleep wakeup in line before the operation that causes the disk i/o error. However, it might be related.
System info:
OS 10.9.2, 16GB RAM, early 2011 MacBook Pro (8,1). 1TB 7200rpm HGST HDD.
I recently installed the new 1TB HGST drive, and used a clone program to migrate all my files over from the old drive. But around the same time I upgraded to Mavericks, and installed a host of new software (the reason for the drive upgrade). My disk i/o problems did not coincide directly with any of these updates, though. S.M.A.R.T checks out as drive verrified. All disk permissions have been fixed multiple times, PRAM zapped.

Answer 1

Thank you so much for your help ruwin  I also kept getting the "Disk I/O error". It only started happening tonight. I had read other things to do - tick "show hidden files, folders, and drives" which I already had ticked. I uninstalled and reinstalled skype. This also did not work. Luckily I found your comment, and it worked! I tried deleting the DbTemp folder, but when I logged into skype it still came up with the error. So I uninstalled my version again, and installed the older version like you said. So thanks heaps, I now have it working again on my laptop. I guess it was just the update, as I had the 6.9 something version on it. I knew it wasn't a problem with my actual "Skype", as it still worked on my iphone. So I figured it had to be a problem with the laptop version. You just saved me a visit to the computer shop  Thanks again!