Do I Have To Keep My Mp3s/Movies In iTunes?

Hello All!!
I have about 40 GB of movies and mp3 files on an external hard disk. In order to transfer these files to my new iPod Touch I copied them into iTunes on my MacBook Pro (where they eventually ended up in the folder /Users/<username>/Music/iTunes/iTunes Media) which has very little disk space.
I have a few questions concerning iTunes and freeing up disk space on my MacBook.
1. Do I have to keep the files that I transferred to my iPod Touch on my MacBook?
2. If I delete the files from iTunes on my MacBook will they be automatically erased from my iPod the next time it performs a sync with iTunes?
3. Could I have made the external drive the location where iTunes stores it's media in order to not occupy disk space on my MacBook?
Thanks!

1 - No
2 - Yes
3 - Hold option when drag and drop to iTunes to create a file path to your external drive
Message was edited by: Malignance

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