Downloaded latest update now Itunes wont open

I just downloaded the latest update. After restart I now cannot open Itunes as I receive the following message when I try to open it:
"Itunes cannot run because it has detected a problem with your Audio Configuration."
This message appears within seconds of double clicking Itunes.
I was playing an older version of Itunes just minutes before the update.
BTW, I am running Microsoft Vista... wonder if that has anything to do with it?
Any help would be deeply appreciated. Thanks.
Dell XPS 410   Other OS  

no, in the case of this error message the problem is typically caused by a broken QuickTime. the article that Jeff linked travhawk too is the first thing to try:
iTunes 7 for Windows: iTunes had detected an audio configuration problem

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