Downloaded update and now it won't open

Yesterday I downlaoded the new iTunes update and now it will not open. I am running Norton and Microsoft Anti-spyware and took some hints from other messages and non of those have worked.
Anyone with ideas to fix this please send them to me and thank you to those who help!!

top fixes for a new iTunes install/upgrade are
- turning off security software such as Norton before the install as Apple suggests
- installing QuickTime standalone, not regular
http://www.apple.com/quicktime/download/standalone.html
- setting up Norton to allow iTunes
- scanning for malware with ewido (Free at www.ewido.net/en/)

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