Drop messages when the application is down

Hello,
We have an application receiving emails from external world. As you know, Exchange server tries to redeliver the message if the application is down or not reachable. Is it possible to configure to drop the emails going to the application if the appliance
is down or not reachable?
Thanks,

Not inherently - you can change the org setting for how long a send connector retries, but that will affect all messages sent outbound.  You may be able to build an Exchange add-on that can add this functionality to your system; or you could add an
SMTP appliance to act as the go-between, and set it so it stops retrying after a shortened interval.

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