Dual G5 frozen even after restart. Mouse & keyboard not responding.

Regarding older Dual G5...recently began using after updating to latest compatible OS ( 10.5.? )...left for dinner... returned to unit frozen, tried re starts, no results...mouse or keyboard not responsive.. have done several re-starts, hard re-starts ( unplugged all ), changed keyboard and mouse, disconnected any 3d party devices... Full screen comes up, window about conflict with "Suitcase"comes up, but keyboard & mouse do nothing???...Clif

Hello,
One way to test is to Safe Boot from the HD, (holding Shift key down at bootup), run Disk Utility in Applications>Utilities, then highlight your drive, click on Repair Permissions, Test for problem in Safe Mode...
PS. Safe boot may stay on the gray radian for a long time, let it go, it's trying to repair the Hard Drive
Reboot, test again.
If it only does it in Regular Boot, then it could be some hardware problem like Video card, (Quartz is turned off in Safe Mode), or Airport, or some USB or Firewire device, or 3rd party add-on, Check System Preferences>Accounts (Users & Groups in later OSX versions)>Login Items window to see if it or something relevant is listed. Or an errant process eating up RAM.
Check the System Preferences>Other Row, for 3rd party Pref Panes.
Also look in these if they exist, some are invisible...
/private/var/run/StartupItems
/Library/StartupItems
/System/Library/StartupItems
/System/Library/LaunchDaemons
/Library/LaunchDaemons

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