Edit in Photoshop "Grayed out"

I have Photoshop CS5 Extended and Lightroom 2.7. When selecting 5 images, right clicking on them and trying to edit them in Photoshop those features are grayed out. Actually all feature which should work with PS are grayed out, but Nik features work.
Actually even just trying to edit one picture is grayed out as well.
Vista 64 bit

http://kb2.adobe.com/cps/401/kb401629.html
Try this, it worked for me. If you are uncomfortable editing you registry you might try uninstalling and reistalling CS5.
Rich

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