Edit in Photoshop no longer works?

I have Lightroom 4.3 with Photoshop 13.1.2 and RAW 7.3 on Mac OS X 10.7.5
I had been using the edit in Photoshop CS6 command in LR to bring my pics into PS with no issues up until just recently, but all of a sudden it stopped working. If I right click an image in LR either from the library or develop module and choose edit in Photoshop CS6 it doesn't do anything. If I close PS and keep it closed, then choose the same command in LR it will start PS, open PS but that's it, it won't open my image. I'm scratching my head on this one.
I uninstalled LR by dragging it to the trash and reinstalled using Adobe Application Manager but that did not make a difference. I don't really want to reinstall PS, but is that the next step?
Does anybody have any advice on what to try? I've checked Adobe updater for anything new and I'm on all the latest.
It's crippled my workflow as I do as much in LR first then bring into PS, so I am having to use PS Camera RAW for now until I get this figured out.
Thanks!

That's interesting and useful. Since Lightroom 3 (which is where I'm at) the changes to Camera Raw have become more important to keeping it in sync with Photoshop. I won't consider an upgrade to one without upgrading the other for that reason. Since it's a Mac and not Windows, which seems to need rebooted for most any change, I'm not sure about the reboot. The only thing I can see a Mac (aka Unix) reboot doing is killing an orphined process or resetting a path. It would be nice to know what fixed it but yes, it's much nicer to actually be using our electronic paper weights.
I didn't look back to see if you reinstalled Photoshop as mentioned but I did write that I think reinstalling software to fix it is just stupid, these aren't programs off a $10 shareware CD and a reinstall is strictly a guess with hope attached.

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