Error 1606 problem

When I try to install Adobe software, I get error message 1606, saying it can't access the Public Shared Pictures location on my external hard drive.  I want to install it on my C drive, which is where all other software installs. Any ideas on how to fix this?

I finally got it fixed - it's been just over 24 hours without any issues. 
I got a number of suggestions on this and several other forums, none of which worked when I tried them, though one of them turned out to be where I needed to be looking.
The suggestion to go to the microsoft website (http://support.microsoft.com/kb/886549) was the most helpful in the end. Mr. Fix-it wouldn't work on Windows 8.1, so I then followed the directions to do it manually.  It indicated this error issue may occur if there is an incorrect setting in one of the following registry subkeys:
•HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\User Shell Folders
•HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\Explorer\User Shell Folders
I made the mistake of assuming it was just referring to software that has been installed, specifically Microsoft products.  I went to those registry subkeys, and found several entries referring to older versions of Office.  I deleted them.  When that didn't resolve it, I went on looking for other solutions. 
Given the installation/un-installation issues were only with Adobe software, I assumed that Adobe was a possible culprit.  I tried a number of suggestions regarding Adobe.  Nothing worked.  As I noted earlier, I tried removing the new HDD to see if that was the issue.  Nothing.
I was getting ready to do a reinstall when I started thinking again about the text of the error message, saying it can't access the Public Shared Pictures location on my external My Cloud device, and showing the wrong IP address.  I went back to the registry subkeys noted above, and looked for registry entries NOT about Microsoft, and NOT about Adobe, but instead ones that might reference the My Pictures folder.  And there I found the problem.  In both registry subkeys, there was one entry that referenced my pictures, and the text of the subkey contained the wrong IP address.  I changed the IP address to the correct one, re-booted, and just like that the issue was fixed!!!!!
A little more time thinking it through would have saved me a whole lot of time searching for solutions.  Live and learn.
Thanks to everyone who offered suggestions!!!  I hope this helps someone else!

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