"Error! Check activation"... What should I do?

I just bought my first epub book from Guilford Press and downloaded ADE for it. However, it won't let me read the book, and only says: "Error! Check activation". What should I do? I am using a regular PC.

I am not a computer specialist and have a real horror from editing my registry (apart from the fact that I think that a program that requires manual registry intervention is not really well programmed). I am confused by two comments in this thread, one says: Just edit the registry manually, the other says you also need to change your Adobe ID. Do I need to create a new ID? Should I also uninstall Digital Editions in between and install it back? Can someone just list down, what I have to do from the entire picture? Currently, I have Digital Editions 4.0.3.110333 installed, I have an authorization which I can not erase with ADE. I run everything with a ThinkPad E530 computer on Windows 7 (including all updates). I have Avira Antivirus Pro installed. Should I cut the internet connection and switch off the antivirus for the work on the registry and the re-authotization or would the re-authorization not work?
Please give detailed instruction so that I can try it without failing.

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