Error code -50 when certain users try to open a document

Got a 17" G5 iMac serving a lab of 14 eMacs. A few users have been having problems accessing items in their home folders. When they try to open a certain recently created document, they get an error message with the code -50. I have identified this as a user parameter list error, but I don't know how to go about correcting it. I have two user groups, and all users and machines in question have the same permissions. I have checked the ownership on affected files--no problem with permissions.

I can open other pdf documents that were scanned then saved to microsoft word. I can't open those in my scanned file.
When I open acrobat reader, I get the same message. I downloade adobe acrobat reader XI to see if that would help and it doesn't I get the same message.
Best regards
Michael Majsak
Director of Marketing & Sales

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Error code -50 when certain users try to open a document

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