Error message -3221 - Could not connect to the I-Tunes Store

I last accessed the I-Tunes store on November 3, 2007 with no problems. The last week of November I received the following error message. "I-Tunes could not connect to the I-Tunes store. An unknown error has occurred (-3221)." I have the latest version of I-Tunes (7.4.3.1). I cleared my DNS server and am sure I-Tunes isn't blocked in my firewall. In fact, I followed all the suggestions given on the I-Tunes diagnostic website. I cannot find any mention of anyone else that has received this particular message. Can anyone help me????

Macafee security center is the culprit.
Open Macafee then: select;
Internet & Network > configure
Firewall > Advanced
Programm Permissions > scroll down to Itunes
Highlight (click on)
Then Grant full access to Itunes.
APPLY then OK
When you select store from Itunes you will need to register with Itunes

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