Error message 'An unknown error occurred (-50)' It repeats this message when I plug my iPhone

When I open iTunes, I get the error message 'unknown error has occurred (-50)' It repeat this message when I plug my iPhone in and it will not let me sync!! Please help, I think this began after an update of iTunes, but it has not resolved after trying to revert to the earlier version.

Hi, Hoofin22. 
Thank you for visiting Apple Support Communities. 
Here are a couple articles that provide some helpful troubleshooting steps for error -50.  Also make sure the most current version of iTunes is installed. 
iTunes Store: "Error (-50)" when downloading purchased content
http://support.apple.com/kb/TS1583
iTunes: Specific update-and-restore error messages and advanced troubleshooting
http://support.apple.com/kb/TS3694
Error 13, 14, 35 and 50 (or -50)
These errors are typically resolved by performing one or more of the steps listed below:
Perform USB isolation troubleshooting, including trying a different USB port directly on the computer. See the advanced steps below for USB troubleshooting.
Put a USB 2.0 hub between the device and the computer.
Try a different Dock Connector or Lightning Connector to USB cable.
Eliminate third-party security software conflicts.
There may be third-party software installed that modifies your default packet size in Windows by inserting one or more TcpWindowSize entries into your registry. An incorrectly set default packet size can cause this error. Contact the software manufacturer that installed the packet-size modification for assistance. Or, follow this article by Microsoft to reset the packet size back to the default for Windows:How to reset Internet Protocol (TCP/IP).
Connect your computer directly to your Internet source, bypassing any routers, hubs, or switches. You may need to restart your computer and modem to get online.
Try to restore from another known-good computer and network.
Hope that helps,
Jason H. 

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