Error message C:\ProgramData\188F1432....DIFxINST32.exe

My iPhone always connected to iTunes OK but now I get message - cannot connect as some software missing - uninstall and re-install.
I have now done this three times and every time I try to open iTunes I get the error message:
File C:\ProgramData\188F1432-103A-4ffb-80F1-36B633C5C9EI\x86\DIFxINST32.exe is not associated with a program - please associate it with a program.
iTunes opens but does not recognise iPhone.
When I use Start/Progammes and enter the above file it shows as does not exist.
In Explorer (set to show hidden files) this file does not appear.
I ran Virus check, Malware check and CCleaner - nothing found.
I urgently need to get iTunes back up as I need to back up my iPhone 4 to transfer stuff onto new iPhone 5.
Any help in resolving this would be appreciated.
I am running Windows 7 Pro.
Many thanks

Update:
I resolved the above error message by restoring an earlier version of that file but iTunes recognises my iPod OK but still says cannot connect iPhone as some software is missing.
iPhone shows in My Computer.
I have stopped and reset Apple Mobile Device to Automatic.
Help please!

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