Error message I'm getting is "Couldn't load XPCOM", when i try to start FF from the Desktop icon

error mssg = "Couldn't load XPCOM" when I click the icon on my desktop to start FF. I don't know what XPCOM is or how to fix it.

Just in case someone else stumbles across this:
I experienced the same problem - no real idea of the cause, though it appeared after an unexplained BSOD on a Vista machine (which in turn happened after I had to clone then swap out my existing C drive - all had been running for a few days after the drive swap - I'm usually 'on' 24/7, but this time period had included several voluntary reboots, so all appeared to be functioning OK after the swap, before the BSOD.
Anyway, after reading many threads similar to this one, my own fix was stupidly simple and has proven to be 100% effective: I simply went to Mozilla and downloaded the current version of Firefox - I then just let it do its own thing and 'upgrade' my current installation, and a few minutes later, Firefox is up and running with all of my setings, add-ins etc fully intact and operational!

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