Error Opening PDF from IE

When I click on a PDF link in a website in Internet Explorer 6, I receive the following error: "There was an error opening this document. This file cannot be found." I can choose to save the file to disk and then it opens normally from there. All our computers here should be configured the same and this works properly on another computer.
This originally occurred using Adobe Reader 8.0.0, so I downloaded and installed 8.1.2 and it still is doing the same thing.
I tried right clicking the link to open in a new window but I am receiving the same message either way.
Any help would be appreciated.
Matthew K.

Check the following registry key:
HKEY_LOCAL_MACHINE\SOFTWARE\Classes\Software\Adobe\Acrobat\Exe
Here check the default value. On an english machine, it has to be set to:
"C:\Program Files\Adobe\Reader 8.0\Reader\AcroRd32.exe"
If you installed Adobe reader to a different directory, enter the path where "AcroRd32.exe" is to be found.

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Check the following registry key:
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For example here below I've got the issue:
http://modemwifi.it/wp-content/uploads/asus-dsl-n55u.pdf
Adobe Acrobat X pro V 10.1.8:
DistributedCOM Error id: 10016 when open pdf from web page.
Nome registro: System
Origine:       Microsoft-Windows-DistributedCOM
Data:          04/11/2013 19:09:19
ID evento:     10016
Categoria attività:Nessuna
Livello:       Errore
Parole chiave: Classico
Utente:        PC-PIERO\Piero
Computer:      Pc-Piero
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Le impostazioni delle autorizzazioni impostazioni predefinite del computer non concedono l'autorizzazione di Attivazione in Locale per l'applicazione server COM con CLSID
{B801CA65-A1FC-11D0-85AD-444553540000}
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< /Event>
How can I solve this problem?
Thanks

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Encountered a strange issue here.
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What happens when you open the Adobe app, then tell it to open the file?
How big are the attachments? There are limitations to the size allowed to be sent:
Email Provider
Size Limit
Gmail
25Mb
Outlook
20Mb
Yahoo
25Mb
Are you sending the files to yourself? Not sure how you are emailing files from a website...
Are the PDF's password-protected, or some kind of copyrighted eBook perhaps? Can you email other files successfully, or are PDF's the only files that don't work?
Perhaps using a free Cloud service as an intermediary might work better.
WyreNut
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Message was edited by: MacNoob0909

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Message was edited by: MacNoob0909

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