Error: "You can't open the application....because it may be damaged or incomplete"

I just wiped a Macbook Pro and freshly installed OS 10.6.3.
I installed CS4 and when you try to open InDesign or Illustrator you get the error message:
"You can't open the application (InDesign or Illustrator) because it may be damaged or incomplete"
Photoshop and Acrobat work fine. What happened to these two?
The Icon to each of these two also have crossed out symbol over them.

This must really be a mystery.  Nearly nothing found using Google.  There seems to be a similar problem with iPhoto that happens and get this error message but no many solutions.
Anyone out there have any suggestions?

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    I attempted to open iPhoto and got this message: you can't open the application because it may be damaged or incomplete. Now the iPhoto icon has a little line through it.
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    1. Back up your iPhoto Library - you should always have a back up anyway.
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    Drag the iPhoto Library from your Pictures Folder to another Disk. This will make a copy on that disk.
    Slightly more complex:
    Use an app that will do incremental back ups. This is a very good way to work. The first time you run the back up the app will make a complete copy of the Library. Thereafter it will update the back up with the changes you have made. That makes subsequent back ups much faster. Many of these apps also have scheduling capabilities: So set it up and it will do the back up automatically. Examples of such apps: Chronosync or DejaVu . But are many others. Search on MacUpdate
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  • When I try to open iPhoto, I get an error message that says it can't open the application because it may be damaged or incomplete.

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    Drag the iPhoto Library from your Pictures Folder to another Disk. This will make a copy on that disk.
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    If you purchased an iLife Disk, then iPhoto is on it.
    If iPhoto was installed on your Mac when you go it then it’s on the System Restore disks that came with your Mac. Insert the first one and opt to ‘Install Bundled Applications Only.
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