Ex2010 -Probem with sending internal and external e-mail

Hi
In night we have a problem with time sync on VMWare Host so our Exchange Environment stopped working. Edge server (Ex 2010 SP3 full update) stopped transfer e-mails to mailbox server (Ex 2010 SP3 full update). After time synchronization e-mails were
treansfered to mailbox server. Users was able to send e-mail inside and outside but after 20-40 minutes users cannot send e-mails - between themselves and outside.
I don't see any e-mails in mailbox queues or using get-messagetrackinlog. I sent e-mail to our test e-mail mailbox on gmail and outlook.com. They wrere not be delivered by mailbox server. I can't find it using get-messagetrackinglog or in mailbox qeue.
What was happen? How to solve this problem?

Hi,
Please disable 3rd party AVs for a little while as Ed mentioned.
Also check whether there is any related error message in App Log.
Thanks
Mavis Huang
TechNet Community Support

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      255.255.255.255  255.255.255.255         On-link     192.168.200.2    261
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      Network Address          Netmask  Gateway Address  Metric
              0.0.0.0          0.0.0.0    192.168.100.1  Default
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