Exchange Mail will not Send mail from Iphone when Desktop computer Shutdown

A client of mine has an Iphone that I have setup to connect to his Microsoft Exchange 2003 Server using Activesync. Everything works fine and dandy until he shutdown his desktop in his office. Than he is no longer able to send any mail from his Iphone but is able to receive it no problem. Anyone have any insight on this problem?

Your problem is with Cox and Cox not having an authenticated SMTP server.
Not many ISPs provide an authenticated SMTP server and I'm not sure why - especially with laptops and devices such as the iPhone so popular.
I'm a Time Warner/RoadRunner customer for cable and internet access and I quit using my RR email account several years ago for this very reason. I switched to using my .Mac account as my primary personal email account which has an authenticated SMTP server. I'm able to send messages with the account regardless the internet service provider used for internet access. My business POP account also has an authenticated SMTP server and no problems sending with this account either - via a number of different Wi-Fi connections and EDGE.
I suggest seriously considering switching to another email account. A Gmail account is free, can be accessed as a POP or IMAP account with the email client on your computer as well as with the iPhone's email client, has a good spam filter at the incoming mail server, and has an authenticated SMTP server.
If you ever move or decide to change your ISP from Cox to a different ISP, your email account and address will not need to change. You can access and send messages with a Gmail account with any ISP - the same with a .Mac account. And you'll have much more server storage space than Cox provides.

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