External mouse and keyboard no longer work after 10.8.5 upgrade

Today I upgraded from OSX 10.8.4 to 10.8.5 on my macbook pro 17". This upgrade caused by external mouse and keyboard to completely stop working. I tried installing the 10.8.5 "combo" install (http://support.apple.com/kb/DL1676) and also tried resetting the PRAM, but neither action had any effect.
I also tried restoring to an older time machine backup with 10.8.4, but could only figure out how to restore files, not the entire system.
I've lost a day of work at this point, I need help... How can I get back to 10.8.4 or get the mouse/keyboard working again on 10.8.5??

Try booting into the Safe Mode.  Disconnect all peripherals except those needed for the test. Shut down the computer and then power it back up. Immediately after hearing the startup chime, hold down the shift key and continue to hold it until the gray Apple icon and a progress bar appear. The boot up is significantly slower than normal. This will reset some caches, forces a directory check, and disables all startup and login items, among other things. When you reboot normally, the initial reboot may be slower than normal. If the system operates normally, there may be 3rd party applications which are causing a problem. Try deleting/disabling the third party applications after a restart by using the application uninstaller. For each disable/delete, you will need to restart if you don't do them all at once.
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