External vs Internal SSD on Mac Pro

Hi,
I'd like to buy a SSD drive for my Mac Pro model 4,1 (2009) Quad 2.66, not to be used for booting OSX but rather audio sample playback. I have a Sonnet PCIe Tempo SATA 6Gb/s installed which I use for eSATA connection to my LaCie d2 drives. Assuming the SSD is a top-performer, I'd like to know if I should connect it to the Sonnet card and have it dangle outside the case, or rather plug it into the spare internal SATA connector which I've heard was available (for the optional second DVD drive) and have it dangle inside. Aesthetics don't matter, it's only a question of performance & possible caveats.
Thanks for your help.

Internal = 250MB/sec max
your PCIe 6G = 500MB/sec
You said "top performer" and you were interested in performance. So that equals buying a 6G SSD in most cases. And your ssd is what depends on where you get the max performance but I assumed you were using an OWC 6G line of SSD
That card has ZERO, NO EFFECT on internal drive bays.
Only affects when you connect something to it.
The card goes to waste a bit on a LaCie D2. And LaCie is one brand I would walk away from. If you do upgrade to Lion, be sure to check about their software and if your D2 is affected.
The Mac Pro internal drive bays (4) all run off and share a common bus channel and less than the advertised "300MB/sec independent for each" that is marketed. It is more like 700MB, not 1GB let alone 1.2GB bandwidth.
Sonnet is bootable. Nice. But you said you don't need that.
NewerTech has a 6G also (two, one supports PM which you don't need)
FirmTek has 6G cards also.
NewerTech MAXPower 6G PCIe eSATA Controller. 2 x eSATA ports w/data transfer rates up to 500MB/s
SeriTek/e6G Snow Leopard 2-Port SATA PCI Express Card for 32/64-bit Macintosh & Windows PC
http://www.firmtek.com/seritek/seritek-e6g/

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