Extra internal hard drive use for all programs in stalled

Question

who to use internal hard drive for programs install?

Answer 1

Kind of hard to figure out what you are asking... Let's assume it's, "How do I install applications on my Mac's second internal hard drive?"
There are two ways applications are installed: Manually and automatically. When you install an application manually, you can just drag it to whatever location you like on whatever volume you like. When an application is installed automatically by an "installer" of some kind, it's going to go, by default, somewhere on the boot volume; most likely in the Applications folder at the root level of the boot volume.
If you're using a late-2012 Mini, there is the extra complication that if you have both a HDD and an SSD installed internally that the OS will attempt to link them into a single Fusion Drive volume. If that's the case, the two drives are treated as a single volume and the OS handles on which physical drive any particular bit (including applications) is actually stored. So if your two physical drives are a single Fusion Drive volume, just don't worry about it.
If your two drives are separate volumes, you can boot from either (assuming you have the OS installed on both volumes) and install applications wherever you like. In many cases, it's a simple matter of dragging-and-dropping to copy an application from one volume to another. Some applications will be happy to run from any location on any volume. Others will run from any location on any volume but will need their various supporting files to be present in the proper places on the boot volume; such supporting files are usually installed by an "installer" but sometimes when the application runs for the first time.
If you need more, or more specific, information, try to form your question in complete sentences and be as clear as you can. Read it back to yourself before pressing the ADD REPLY or SUBMIT buttons to be sure it's something another person will understand.