"File is already open or in use by another application"

I get "File is already open or in use by another application" when opening a PDF in Acrobat and Reader. Only happens intermittently.Files are on a network share.
It doesn't seem to happen as often if Acrobat/Reader are already running. Sometimes it works on the 2nd try, other times it takes upwards of 7 or 8. Not entirely sure if this is an Adobe issue as I've completely reinstalled both programs.
Any help would be appreciated. Thanks.
Ben

Jenifer,
I've been dealing with this problem for a year, and it is a big time waster. Here is a solution someone gave me which resolves the problem. However, there is a tradeoff- one problem for another.
There is a file named aiicon.dll in Program Files > Common Files > Adobe > Shell. If you rename this file to aiiconold.dll (don't delete it), the problem with saving and deleting files will be resolved. However, the tradeoff is that you will lose your Illustrator thumbnails for your AI files. See for yourself. I've been doing it this way for a month or two, and I can live without the thumbnails most of the time. The nice thing about renaming the aiicon.dll file is that you can go back to the original name anytime, and everything will be as it was in the beginning.
I guess Illustrator has an incompatibility issue with the new operating systems. I don't think there are any perfect solutions. But I keep looking. I am as frustrated with AI as you are.

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