Files On Desktop Suddenly Frozen And Won't Open ??

I was writing a reply to the forum half an hour ago and needed to open a file on my desktop.
It refused to open. I can drag it about but not open it.
All the other files on the desktop are similarly frozen or dead.
The Dock appears OK and I can open programs.
I restarted the computer to no avail.
I switched it off and disconnected the power, but when it was switched on again the desktop files are still frozen. I can highlight them but not open them.
Any ideas?
PS. I can access the files by going into my users folder in the Dock, selecting the Desktop folder and opening the files from there.
Message was edited by: Ian R. Brown

More Info:-
I have run Verify Disk and Repair Disk Permissions to no avail.
Thinking back over the past few weeks I had noticed some slightly unusual behaviour which may have been building up to this.
When I started up the computer the icons would all appear on the desktop and then some of them would appear to "flash" slightly as though they were not at full brightness to begin with.
Also when I opened a folder, sometimes the icons inside would hesitate before appearing.
These symptoms were so slight that I took no real notice of them ...... I was just vaguely aware they were occurring.
I also seem to recollect on occasions, certain desktop folders not opening the first time they were double-clicked, but they always worked soon after so I thought nothing of that ........ putting it down to a temporary glitch.
An hour before this freeze occurred I had replaced the Mighty Mouse with an old Logitech wireless one and at first thought that might be the cause, but swopping back to the Mighty Mouse changed nothing!

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