Flash will not launch unless Mac is booted in Safe Mode

This Flash app. is part of Adobe MC CS5 Suite. The computer is iMac with latest update. All updates recent on CS5. All other apps. in suite are good.
Flash launch hangs when initializing Tools. After about 10 minutes it completes it's launch but frequently crashes after awhile.
I have deleted the plist, uninstalled/reinstalled. The only way it will work is if I boot the iMac in Safe Mode.
Any thoughts?

You are SO right! I discovered Wednesday there were
TONS of fonts installed over the summer from the Folio Collection. They were inside a  folder within the Fonts folder and I didn't go far enough down the fonts list to get to "F" where they ended up alphabetically.
You get the prize.
What is still a mystery is why Flash reacted to excessive fonts and not the other apps. in the Collection? I will, however, not lose sleep over this.

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