Flashing screen when trying to save a file

When i tried to save a file from Microsoft, when the screen popped up to show the possible folders to save, it started to flash at the folder preview (not the whole preview but half from mid point to bottom of the display). It was very lagging when scrolling down even though I still have almost 1GB of free memories. Most of the time I can't scroll anymore so I have to save the file somewhere without a folder and then drag to the desired folder in Finder. What should I do here?

Save the file as a new name. Close and Open the new file.
Most likely when a file transfer happens, Office makes the file 'Read Only'.
If you have two opened files with the same name, the last opened file will be 'Read Only'.

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