Fresh install won't start - says it's already running even after reboot

I've installed Firefox for the first time on this Windows 2008 machine.
The installer quit complaining that Firefox was already in use. I've rebooted twice, and attempted to delete the parent.lock file, and it still won't open.
I can't delete the parent.lock file as it's in use, even after a reboot.
Anyone got any ideas how I fix this?

edit
I missed the post above. Partly no doubt the annoying lag on forum listings updates.
Is the entry in the ''profiles.ini'' file sane and does it point at a location that has suitable read and write permissions. I am of course assuming if you rename ''profiles.ini'' in its current location that Firefox does recreate it.
* http://kb.mozillazine.org/Profiles.ini_file
Presumably after you delete or rename the profile folder Firefox does manage to recreate and populate the profile.
If this is not happening do a clean reinstall of Firefox again, deleting all the Firefox program folders and files prior to the install.
*[[Troubleshoot and diagnose Firefox problems#w_5-reinstall-firefox]]_5-reinstall-firefox

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