FYI: TrendMicro antivirus prevents Transport Service from starting after installing Echange Server 2013 Service Pack 1

I installed Exchange Server 2013 SP1 in my test environment. After that mail flow between internal and external mail servers completely stopped. In the end I discovered that Transport Service on both of the mailbox servers refused to start (or, to be more
exact, stopped shortly after starting).
The following events appeared in the System event log:
Event ID 1052 (error)
Source: MSExchange Extensibility
Message: Failed to create agent factory for the agent 'ScanMail SMTP Receive Agent' with error 'Failed to create type 'TrendMicro.SMEX.hookE12TransportAgent.hookE12SmtpReceiveAgentFactory' from assembly 'C:\Program Files\Trend Micro\Smex\hookE12TransportAgent.dll'
due to error 'type not found'.'. Please verify the corresponding transport agent assembly and dependencies with correct version are installed.
Event ID 16023 (error)
Source: MSExchangeTransport
Message: Microsoft Exchange couldn't start transport agents. The Microsoft Exchange Transport service will be stopped. Exception details: Failed to create type 'TrendMicro.SMEX.hookE12TransportAgent.hookE12SmtpReceiveAgentFactory' from assembly 'C:\Program
Files\Trend Micro\Smex\hookE12TransportAgent.dll' due to error 'type not found'. : Microsoft.Exchange.Data.ExchangeConfigurationException: Failed to create type 'TrendMicro.SMEX.hookE12TransportAgent.hookE12SmtpReceiveAgentFactory' from assembly 'C:\Program
Files\Trend Micro\Smex\hookE12TransportAgent.dll' due to error 'type not found'.
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.FactoryTable.CreateAgentFactory(AgentInfo agentInfo)
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.FactoryTable..ctor(IEnumerable agents, FactoryInitializer factoryInitializer)
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.RuntimeSettings..ctor(MExConfiguration config, String agentGroup, FactoryInitializer factoryInitializer)
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.MExRuntime.Initialize(String configFile, String agentGroup, ProcessTransportRole processTransportRole, String installPath, FactoryInitializer factoryInitializer)
   at Microsoft.Exchange.Transport.Extensibility.AgentComponent.Load()
Event ID 701 (informational)
Source: MSExchangeTransport
Message: The service will be stopped. Reason: Microsoft.Exchange.Transport.TransportComponentLoadFailedException: Loading of component 'SmtpReceiveAgents' failed. ---> Microsoft.Exchange.Transport.TransportComponentLoadFailedException: The agent component
failed to load. ---> Microsoft.Exchange.Data.ExchangeConfigurationException: Failed to create type 'TrendMicro.SMEX.hookE12TransportAgent.hookE12SmtpReceiveAgentFactory' from assembly 'C:\Program Files\Trend Micro\Smex\hookE12TransportAgent.dll' due to
error 'type not found'.
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.FactoryTable.CreateAgentFactory(AgentInfo agentInfo)
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.FactoryTable..ctor(IEnumerable agents, FactoryInitializer factoryInitializer)
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.RuntimeSettings..ctor(MExConfiguration config, String agentGroup, FactoryInitializer factoryInitializer)
   at Microsoft.Exchange.Data.Transport.Internal.MExRuntime.MExRuntime.Initialize(String configFile, String agentGroup, ProcessTransportRole processTransportRole, String installPath, FactoryInitializer factoryInitializer)
   at Microsoft.Exchange.Transport.Extensibility.AgentComponent.Load()
   --- End of inner exception stack trace ---
   at Microsoft.Exchange.Transport.Extensibility.AgentComponent.Load()
   at Microsoft.Exchange.Data.Directory.ADNotificationAdapter.RunADOperation(ADOperation adOperation, Int32 retryCount)
   at Microsoft.Exchange.Data.Directory.ADNotificationAdapter.TryRunADOperation(ADOperation adOperation, Int32 retryCount)
   at Microsoft.Exchange.Transport.SequentialTransportComponent.Load()
   --- End of inner exception stack trace ---
   at Microsoft.Exchange.Transport.SequentialTransportComponent.Load()
   at Microsoft.Exchange.Transport.Components.Activate()
The reason for that behavior was TrendMicro ScanMail for Exchange 11. Seems that it was unable to work with the new SP properly and prevented the entire Transport Service from starting. Uninstallation of the antivirus eliminated the issue.

Actually, you can just disable the agents until TrendMicro releases a patch and then enable them again:
http://community.trendmicro.com/...
BTW, a similar problem (high CPU utilization and services not starting) is hitting the AVG package:
http://forums.avg.com/..
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Memory Module: BANK 0/DIMM1, 2 GB, DDR3, 1067 MHz, 0x80AD, 0x484D54313235533642465238432D47372020
Memory Module: BANK 1/DIMM1, 2 GB, DDR3, 1067 MHz, 0x80AD, 0x484D54313235533642465238432D47372020
AirPort: spairport_wireless_card_type_airport_extreme (0x168C, 0x8F), Atheros 9280: 4.0.55.4-P2P
Bluetooth: Version 2.5.0f17, 2 service, 19 devices, 1 incoming serial ports
Network Service: Ethernet, Ethernet, en0
Network Service: AirPort, AirPort, en1
Serial ATA Device: WDC WD5000AAKS-40V2B0, 500.11 GB
Serial ATA Device: HL-DT-ST DVDRW GA11N
USB Device: EyeTV Hybrid, 0x0fd9, 0x0027, 0x24300000 / 3
USB Device: Built-in iSight, apple_vendor_id, 0x8502, 0x24400000 / 2
USB Device: iPod, apple_vendor_id, 0x1299, 0x26200000 / 3
USB Device: Internal Memory Card Reader, apple_vendor_id, 0x8403, 0x26500000 / 2
USB Device: IR Receiver, apple_vendor_id, 0x8242, 0x04500000 / 2
USB Device: BRCM2046 Hub, 0x0a5c (Broadcom Corp.), 0x4500, 0x06100000 / 2
USB Device: Bluetooth USB Host Controller, apple_vendor_id, 0x8215, 0x06110000 / 4

There was a fix suggested over on this thread. I didn't want to re-post the answer since it is not mine - rather it was my thread with the same question.
https://discussions.apple.com/message/15735275

FYI: TrendMicro antivirus prevents Transport Service from starting after installing Echange Server 2013 Service Pack 1

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