Get "Open With Box" recommending open with internet explorer

After I downloaded 4.0, ti appeared that a virus or trojan horse came also. It was "running a scan and asking for me to purchase the program. I ran a scan with software I had and got rid of it, no when I try to open programs I get the "Open with box and recommended to open with IE, but it will not open the programs, get in a loop of open with, run program, open with ect.

If you have access to a mouse, try using it. If everything is okay using the mouse, then it is likely trackpad related. Other troubleshooting.
Try setting up another admin user account to see if the same problem continues. If Back-to-My Mac is selected in System Preferences, the Guest account will not work. The intent is to see if it is specific to one account or a system wide problem. This account can be deleted later.
Isolating an issue by using another user account
If the problem is still there, try booting into the Safe Mode.  Shut down the computer and then power it back up. Immediately after hearing the startup chime, hold down the shift key and continue to hold it until the gray Apple icon and a progress bar appear. The boot up is significantly slower than normal. This will reset some caches, forces a directory check, and disables all startup and login items, among other things. If the system operates normally, there may be 3rd party applications which are causing a problem. Try deleting/disabling the third party applications after a restart by using the application unistaller. For each disable/delete, you will need to restart if you don't do them all at once.
Safe Mode
Safe Mode - About
General information.
Isolating issues in Mac OS X
Troubleshooting Permission Issues
Step by Step to Fix Your Mac

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