Getting error message "Could not open a scratch file...

...because the file is locked. Use the "Properties" command in Windows explorer to unlock the file"
I cannot open PS because of this error message.  I changed the scratch disk within Photoshop in the "Preferences" section and next time I opened PS (CS4) this is the error message I got.
I went to Windows Explorer and all my permissions are "Full Control" on all users.  I cannot see anything else I can do.  How do I solve this problem?
PS CS4
Windows Vista/home 32

Are you running PS as administrator?
Also try clearing your perf file by selecting CTRL, Alt, Shift during PS Start up. You have to be quick with the open timing. A screen should pop up asking if you want to reset. Hit yes. A conformation should pop up after.

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